Glutathione S-Transferase Mu2 (GSTM2) Antibody MBS4380580 from MyBioSource.com

Product Specs
ItemGlutathione S-Transferase Mu2 (GSTM2) Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS4380580
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ApplicationsImmunofluorescence (IF), Immunohistology (Formalin-Fixed)
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
ReactivityHuman. Others not tested
TargetGlutathione S-Transferase Mu2 (GSTM2)
IsotypeIgG1
Molecular WeightPredicted: 26kDa
Observed: 28kDA
CloneCPTC-GSTMu2-2
HostMouse
ImmunogenMembers of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, namely alpha, zeta, theta, kappa, u, pi, sigma and omega, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. GSTM2 is specific for muscle hence the alternate name GST muscle antibody
NCBI Full Gene Nameglutathione S-transferase mu 2
NCBI Gene AliasesGST4, GSTM, GSTM2-2, GTHMUS
ClonalityMonoclonal